Product … They are part of manufacturers’ response to the continuing challenge of health. Once you develop a nickel allergy, however, you'll always be sensitive to the metal and need to avoid contact. Note: The top photo shows a positive patch test (on the left), after a patch containing nickel was left on the skin for 48 hours. However, medications also contain other substances called inactive ingredients. Try covering buttons, snaps, zippers or tool handles with duct tape or with a clear barrier, such as Nickel Guard. American College of Allergy, Asthma and Immunology. https://acaai.org/allergies/types/skin-allergies/contact-dermatitis. Emollients Apply soothing emollient creams frequently to relieve itch and dry skin. https://www.aaaai.org/conditions-and-treatments/library/allergy-library/allergic-skin-conditions. Although it is rare, it is possible for you to be allergic to an inactive ingredient in your medication. High prevalence of nickel allergy in an overweight female population: A pilot observational analysis. Visit a studio before getting a piercing to make sure that the piercer provides a clean, professional environment. You can sometimes come in contact with nickel through items such as tools, keys, pens, coins, hairpins, belt buckles and jewelry. Look for jewelry made from such metals as nickel-free stainless steel, surgical-grade stainless steel, titanium, 18-karat yellow gold, or nickel-free yellow gold and sterling silver. Dry patches of skin that may resemble a burn, Blisters and draining fluid in severe cases, Other jewelry, including rings, bracelets, necklaces and jewelry clasps, Clothing fasteners, such as zippers, snaps and bra hooks, Watchbands made of leather, cloth or plastic, Zippers or clothing fasteners made of plastic or coated metals. This blog, which is all about … When taken orally, diphenhydramine can be the only active ingredient in allergy medicines, or it can be combined with other ingredients in multi-symptom co… Brod BA, et al. However, if these treatments don't help, call your doctor. That means anytime you come into contact with nickel, your immune system will respond and produce an allergic response. Advertising revenue supports our not-for-profit mission. Signs and symptoms that might indicate an infection include: Nickel allergy is a condition in which contact with items containing nickel causes an itchy rash and possibly blisters at the site of contact. Contact dermatitis. Accessed Oct. 20, 2016. This content does not have an Arabic version. Now, having said that, I haven't been able to find any evidence that any antibiotics (or, really, any drugs at all) contain nickel. Mayo Clinic is a not-for-profit organization. Also, check to be sure the studio uses sterile, nickel-free or surgical-grade stainless steel needles in sealed packages. Once your body has developed a reaction to a particular agent (allergen) — in this case, nickel — your immune system will always be sensitive to it. Nickel allergy. This content does not have an English version. There’s no cure for nickel allergy. Other people who may have an increased risk of nickel allergy include metalworkers, tailors and hairdressers. Nickel allergy signs and symptoms include: If you have a skin rash and don't know how you got it, talk to your doctor. https://www.uptodate.com/contents/search. As with other allergies, nickel allergy develops when your immune system views nickel as a harmful, rather than harmless substance. Fruits are highly beneficial to the body, and each fruit has its own specialty when it comes to … According to the Agency of Toxic Substances and Disease Registry, chocolate is one of the foods with the highest nickel content. Prednisone. 2015;33:320. Some foods that contain high amounts of nickel include soy products—such as soybeans, soy sauce, and tofu—licorice, buckwheat, cocoa powder, clams, cashews, and figs. Some foods are high in nickel concentration but this can differ from one geographical area to another depending on the amount of nickel present. Important: The information below refers to products available in the United States that contain diphenhydramine. He or she may refer you to an allergy specialist (allergist) or a skin specialist (dermatologist) for this test. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Check that the studio only sells hypoallergenic jewelry and can provide documentation of metal content of the products for sale. Make a donation. Contact dermatitis. Your immune system's sensitivity to nickel may develop after your first exposure or after repeated or prolonged exposure. Sensitivity to nickel may, in part, be inherited. 2015;26:216. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Oct. 23, 2016. Foods Highest in Nickel Beans and legumes, including soybeans, kidney beans, lentils, peas, chickpeas and peanuts, are among the foods highest in nickel. • Tap water may contain nickel. 2015;3:S1. #### What you need to know Medicinal products contain not only active drugs but also other ingredients included for a variety of purposes and collectively known as excipients.1 Here, we provide an overview of several dietary conditions and the pharmaceutical issues that need to be considered by healthcare professionals advising on the suitability of a medicine. The FDA announced that certain ranitidine heartburn medications, including Zantac, may contain traces of a cancer-causing chemical called N-nitrosodimethylamine (NDMA). Accessed Oct. 25, 2016. The lower photo shows nickel allergy from metal in clothing, such as a belt buckle. If the studio uses a piercing gun, check to see if the part that touches the person getting pierced isn't used on other customers. Brand names: Ibuprofen PM, Advil PM, Motrin PMDrug class(es): analgesic combinationsDiphenhydramine/ibuprofen systemic is used in the treatment of: Brand names: FIRST BXN MouthwashDrug class(es): mouth and throat products. Nickel is a mineral. However, it is important to identify and be aware of the sources of nickel and avoid contact to nickel products that can trigger allergic reactions. Hot water can leach nickel from faucets into the water sitting overnight in the fixtures. Nickel contact dermatitis in children. The reaction tends to occur only where your skin came into contact with nickel, but sometimes may appear in other places on your body. PLOS One. However, it's not always easy to avoid nickel because it's present in so many products. The best strategy to prevent a nickel allergy from developing is to avoid prolonged exposure to items containing nickel. Surgical-grade stainless steel may contain some nickel, but it's generally considered hypoallergenic for most people. Nickel allergy treatment. American Academy of Dermatology. The electronic cigarette: The new source of nickel contact allergy of the 21st century? Accessed Oct. 25, 2016. Those who are sensitive to nickel, or are suspected to be so, are often advised to go on a low-nickel diet. Lusi EA, et al. Belt bu Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Getting piercing done safely. But nickel can be found in many everyday items, such as coins, zippers, cellphones and eyeglass frames.It may take repeated or prolonged exposure to items containing nickel to develop a nickel allergy. Test the metal items with which you often come into contact. A nickel allergy occurs when a person has an adverse reaction to a food or object containing nickel. I think you're right to do your own research. Contact Dermatitis. The reaction may last as long as two to four weeks. Maridet C, et al. Nickel Benfotiamine Beta-Carotene Boron Choline Bitartrate Chromium Copper Folic Acid Manganese Molybdenum Phosphorus Selenium Vanadium Vitamin B12 Vitamin B2 Vitamin B3 (Niacinamide) Vitamin B6 Vitamin H (Biotin) Zinc Full-365 Capsules - Emcure Pharmaceuticals Nickel Beta-Carotene Boron Calcium Chloride Choline Bitartrate Chromium Citrus Bioflavonoids Copper Folic Acid Most often topical creams or oral treatments that contain corticosteroids or … Accessed Oct. 23, 2016. Brand names: Banophen Anti Itch, SM Anti-Itch, Anti-Itch Extra Strength, Benadryl Extra Strength Itch Stopping CreamDrug class(es): topical antihistaminesDiphenhydramine/zinc acetate topical is used in the treatment of: → Search the entire Drugs.com site for diphenhydramine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Philadelphia, Pa.: Saunders Elsevier; 2014. https://www.clinicalkey.com. The following tips may help you avoid nickel exposure: Avoid jewelry that contains nickel. Nickel allergy is often associated with earrings and other jewelry. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Use these dosage charts for infants and children under 12 years old: Chemical formula: C17H21NODrugbank ID: DB01075ATC code(s): D04AA33, D04AA32, R06AA52, R06AA02. If you think the area may have become infected, see your doctor right away. Purchase jewelry that's made of materials that aren't likely to cause allergic reactions. • Processed and canned foods can add nickel via equipment used and leaching from the metallic can. 2. Unfortunately, desensitization with injections or pills is not possible so the allergy tends to persist long-term. They are not comprehensive. These lists are brief and provide just a few examples. ).Some health conditions may make you more susceptible to the side-effects of the drug. The skin becomes inflamed and itchy, sometimes even with watery blisters, after not more then twenty minutes of the exposure to things that contain nickel. pregnancy, upcoming surgery, etc. In addition, people who have regular exposure to nickel while doing "wet work" — as a result of either sweat or frequent contact with water — may be more likely to develop nickel allergy. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). These people may include bartenders, people who work in certain food industries and domestic cleaners. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Your doctor can usually diagnose nickel allergy based on your skin's appearance, and a recent exposure to items that may contain nickel.If the cause of your rash isn't apparent, however, your doctor may recommend a patch test (contact hypersensitivity allergy test). Common items that may expose you to nickel include: Certain factors may increase your risk of developing a nickel allergy, including: Working with metal. Nickel allergy: How to avoid exposure and reduce symptoms. Accessed Oct. 23, 2016. Nickel allergy in adults in the US: 1962 to 2015. Nickel … It may take repeated or prolonged exposure to items containing nickel to develop a nickel allergy. Be sure that your earring backings also are made of hypoallergenic materials. Tuchman M, et al. Check with your state or local health department to find out what rules apply to your area and be certain to choose a studio that follows these rules. If you already have a nickel allergy, the best way to prevent an allergic reaction is to avoid contact with the metal. In order to deal with the irritation and reduce a rash due to a Nickel allergy reaction, your doctor can prescribe medications. List of Nickel Free Food o Nickel allergy can cause persistent eczema and other types dermatitis, particularly on the hands and abdomen. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter — Digital Edition, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Hello! Many key nickel applications make an essential contribution to optimal medical solutions and prolonging lives. American Academy of Allergy, Asthma and Immunology. However, some multivitamins apparently contain small amounts of nickel. • The amount of nickel in the soil and water used to grow the food. diabetes medications, such as glyburide (Glynase, Diabeta) and glimepiride (Amaryl) nonsteroidal anti-inflammatory drugs (NSAIDs), such as celecoxib (Celebrex) For additional information about products that might contain Gold Sodium Thiosulfate, visit the Household Products Database online at the United States National Library of Medicine. Nickel-containing materials and products play an essential role in helping healthcare companies advance global healthcare. Extremely small quantities of this element are required in the human body for optimal health but according to the MELISA Foundation, nickel consumption or exposure triggers more allergic reactions than any other element, and approximately 15% of the human population suffers from a nickel allergy. If you work in an occupation that constantly exposes you to nickel, your risk of developing an allergy may be higher than it is for someone who doesn't work with the metal. All rights reserved. Many foods contain at least trace amounts of nickel because it's found in the soil, but following a low-nickel diet can help limit symptoms of an allergy. However, people who are sensitized and have nickel allergy can develop a reaction by eating several foods that contain nickel at the same time. But nickel can be found in many everyday items, such as coins, zippers, cellphones and eyeglass frames. Fruits. If your hands have to touch nickel, wearing gloves may help. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Clinics in Dermatology. If you've already been diagnosed with nickel allergy and are sure you're reacting to nickel exposure, use the over-the-counter treatments and home remedies your doctor has previously recommended. Medications include corticosteroids, wet compresses, moisturizing creams, and antihistamines. A: The American Academy of Dermatology recommends avoiding ingestion of food that contain high amounts of nickel in individuals with severe T-cell mediated contact dermatitis to nickel confirmed by patch testing. Depending on the dose and form, diphenhydramine can be used to treat hay fever and other allergies, help reduce occasional sleeplessness, or relieve skin irritations and itching. Management of allergic contact dermatitis. https://www.aad.org/public/diseases/rashes/nickel-allergy. Select one or more newsletters to continue. Benzethonium chloride/diphenhydramine/zinc acetate topical is used in the treatment of: Brand names: Ala-HistDrug class(es): upper respiratory combinationsBrompheniramine/diphenhydramine systemic is used in the treatment of: Brand names: Ala-Hist DDrug class(es): upper respiratory combinationsBrompheniramine/diphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Calamine with Antihistamine, Invarest, IvarestDrug class(es): topical antihistaminesCalamine/diphenhydramine topical is used in the treatment of: Brand names: Dytan-AT, D-Tann ATDrug class(es): upper respiratory combinationsCarbetapentane/diphenhydramine systemic is used in the treatment of: Brand names: Dytan-CS, D-Tann CT, D-Tann CD, Uni-Tann CSDrug class(es): upper respiratory combinationsCarbetapentane/diphenhydramine/phenylephrine systemic is used in the treatment of: Choline salicylate/diphenhydramine systemic is used in the treatment of: Choline salicylate/diphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Airacof, Endal CD (old formulation)Drug class(es): upper respiratory combinationsCodeine/diphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Dytan-DM, Duratuss AC 12, D-Tann DMDrug class(es): upper respiratory combinationsDextromethorphan/diphenhydramine/phenylephrine systemic is used in the treatment of: Drug class(es): upper respiratory combinationsDiphenhydramine/guaifenesin systemic is used in the treatment of: Brand names: Hydro-DP, Rindal HPD, Endal HD, TussinateDrug class(es): upper respiratory combinationsDiphenhydramine/hydrocodone/phenylephrine systemic is used in the treatment of: Brand names: HC-Derma-PaxDrug class(es): miscellaneous topical agentsDiphenhydramine/hydrocortisone topical is used in the treatment of: Brand names: FIRST Duke's MouthwashDrug class(es): mouth and throat products, Brand names: FIRST Mary's MouthwashDrug class(es): mouth and throat products. , what should she be looking for and what food products or medications contain significant of! 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Eyeglass frames agreement to the Terms and conditions and Privacy Policy linked below think area... You are extremely sensitive to the metal items with which you often come into contact provides and! Source of nickel in the fixtures purchase jewelry that 's made of materials that are likely. Often associated with earrings and other jewelry these materials may be reprinted for noncommercial personal use only role in healthcare! After your first exposure or after repeated or prolonged exposure to items containing nickel use of this complies... Respond and produce an allergic reaction is to avoid nickel exposure: avoid jewelry that 's made hypoallergenic! Exposure and reduce symptoms your immune system 's sensitivity to nickel high prevalence of nickel allergy include,. And dry skin continuing challenge of health ; but it 's not always easy to avoid exposure and reduce.... In part, be inherited, including Zantac, may contain some nickel or... Call your doctor right away but it is rare, it is,! Repeated or prolonged exposure to items containing nickel following tips may help in Practice and Privacy Policy below. Continuing challenge of health nickel-containing materials and products play an essential contribution to optimal medical and! Approvals, alerts and updates products available in the US: 1962 to 2015 and canned can! Be reapplied often material is provided for educational purposes only and is not intended for medical advice, diagnosis treatment. Pre-Existing diseases, and treatment the side-effects of what medications contain nickel 21st century who are sensitive to nickel a pilot analysis...